Nocturnal asthma: Understanding chronobiology and chronotherapy
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چکیده
منابع مشابه
Chronobiology of and Chronotherapy for Rheumatoid Arthritis
For instance, ICR mice, which were housed under standardized light-dark cycle conditions (lights-on and lights-off at 7:00 and 19:00, respectively) at a room temperature of 24 ± 1oC (range) and a relative humidity of 60 ± 10% (range) and were allowed free access to food and water displayed a circadian rhythm in their leukocyte counts with a peak at noon and a trough at midnight (Fig. 1). Many o...
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Advancements in chronopharmaceutics, the traditional goal of pharmaceutics is becoming obsolete. Until now, the emphasis has been on formulations that maintain constant drug levels throughout the day. But we now need to develop more biologically appropriate formulations that take account of variations in bodily functions, such as blood pressure, asthma, arthritis, duodenal ulcer, cancer, diabet...
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The development of solid-phase peptide synthesis in the early 1960s and recombinant DNA technology in the early 1970s boosted the scientific interest of utilizing proteins and peptides as potential therapeutic agents to battle poorly controlled diseases. While there has been rapid progress in the development and synthesis of new proteins and peptides as potential therapeutic agents, the formula...
متن کاملAdrenaline and nocturnal asthma.
OBJECTIVE To determine whether the nocturnal fall in plasma adrenaline is a cause of nocturnal asthma. DESIGN Double blind placebo controlled cross-over study. In the first experiment the nocturnal fall in plasma adrenaline at 4 am was corrected in 10 asthmatic subjects with an infusion of adrenaline after parasympathetic blockade with 30 micrograms/kg intravenous atropine. In the second expe...
متن کاملKetotifen and nocturnal asthma.
Patients with asthma often wheeze at night and they also become hypoxic during sleep. To determine whether ketotifen, a drug with sedative properties, is safe for use at night in patients with asthma, we performed a double blind crossover study comparing the effects of a single 1 mg dose of ketotifen and of placebo on arterial oxygen saturation (SaO2), breathing patterns, electroencephalographi...
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ژورنال
عنوان ژورنال: Allergology International
سال: 1997
ISSN: 1323-8930
DOI: 10.2332/allergolint.46.17